Ball State's lone win on the day came at No. 3 doubles while Notre Dame swept the singles competition.
Sophomores Lucas Andersen and Matt Helm defeated Wyatt McCoy and Kenneth Sabacinski of the Fighting Irish 6-2.
In singles play, the closest match of the day was at No. 1 singles, where Andersen was ultimately defeated by Quentin Monaghan 6-4, 7-5.
The Cardinals will return to the court on Feb. 13 as they host Xavier at 2 p.m.